INFLUENCE OF THE COMPOSITION OF “VOLCANO MINERAL” PLANTAND ANIMAL RAW MATERIALS ON HUMORAL AND CELLULARSTRUCTURE OF THE IMMUNE SYSTEM

Abstract

Objective. To study the influence of the composition of “Volcano mineral” plant and animal raw materials on the immune
system of research animals
Materials and Methods: The study was conducted at the Center of the Research Laboratory of the NC JSC “SMU”. To
assess cellular and humoral immunity, research animals were divided into 4 groups of 10 rats in each group. During the
experiment, rats were exposed to acute (7 days) and chronic (21 days) smoke exposure for 5 minutes with “Volcano-mineral”
burning at a dose of 10 mg, 20 mg, and 30 mg.
Results: exposure to plant and animal raw materials known as “Volcano mineral” was shown to cause both acute and
chronic increases in the quantity of circulating immune complexes. T-lymphocytes and T-suppressors were increased at
acute and decreased at chronic exposure to the “Volcano-mineral” substance at a dose of 10 mg. There was observed a
decrease in phagocytic activity during exposure to “Volcano-mineral” in doses of 20 and 30 mg, an increase in the indicators
of T-helper in the dose of 20 mg, leukocytes and B-lymphocytes in the dose of 30 mg. A significant increase in the level of
immunoglobulin A was found in acute and chronic exposure to “Volcano-mineral” at a dose of 20 mg and an increase in
acute exposure at a dose of 30 mg. At chronic exposure to smoke from the “Volcano-mineral” substance at a dose of 30 mg
a significant decrease in immunoglobulin G was observed.
Conclusion. Acute exposure to the “Volcano mineral” substance's smoke causes a shift in the body's cellular immune
response, which in turn causes a protective immunological response. Higher doses over time have been shown to have an
immunosuppressive impact.