ANALYSIS OF CORRELATION AND REGRESSION RELATIONSHIPS BETWEEN THYROID DYSFUNCTION, ADRENAL DYSFUNCTION AND CARDIOPULMONARY DISORDERS IN PATIENTS WITH DIABETES MELLITUS

Abstract

Introduction: Diabetes mellitus is a widespread non-communicable disease with a significant impact on public health. The study aimed to investigate the interrelationships between hormonal-metabolic and cardiorespiratory disorders in patients with type 2 diabetes mellitus (T2DM). Materials and methods: Study design - longitudinal cohort study of correlation and regression analyses to assess the relationship between various morphometric parameters of the thyroid gland, adrenal glands and respiratory function. A total of 175 patients with T2DM were included in the study, classified into subgroups based on body mass index (BMI). Research period: 03.01.2024-02.05.2024. Results: The study revealed strong correlations between thyroid and adrenal gland parameters in all patient groups. Additionally, significant associations were found between lung function indicators and insulin resistance index (IRI). Regression analysis confirmed these relationships and provided insights into the functional dependencies between these parameters. Conclusions: The findings highlight the complex interplay between hormonal-metabolic and cardiorespiratory systems in T2DM. These interrelationships emphasize the importance of a comprehensive approach to managing diabetes, considering not only metabolic control but also the impact on other organ systems. Further research is needed to elucidate the underlying mechanisms and develop targeted interventions.